The national security thought, system and strategy in the new era are interconnected and complementary, which are three important dimensions for understanding the innovation of the holistic approach to national security. The first innovation of the holistic approach to national security lies in the innovation of thought, which leads the transformation of the national security thinking mode with the integrated logic of systematic coordination, focusing on the overall goal of “ten principles to adhere to”, discerning the complex internal and external environment and practice with the overall security benefits as the standard, and promoting all parties and the whole society to participate in maintaining national security. Secondly, the pioneering ideological innovation leads the innovation of formal and informal security systems. In the past ten years, China has established a national security system that takes into account both internal and external factors and integrates multiple functions, as well as a centralized, unified, efficient mechanism with “the Partys leadership over the security sector”, and has embarked on a path of national security with Chinese characteristics featured by the “five principles to adhere to”. Finally, innovation in the thought and system jointly promote the innovative coordination of Chinas “grand strategy”, for which we strive to pursue development and safeguard security, build a new development pattern, enhance the security and stability of economic development, and form new quality productive forces. It is necessary to safeguard Chinas new development pattern with a new security architecture and achieve virtuous interaction between highquality development and highlevel security.